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Clinical trials for Central Venous Catheter

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    104 result(s) found for: Central Venous Catheter. Displaying page 1 of 6.
    1  2  3  4  5  6  Next»
    EudraCT Number: 2012-002469-37 Sponsor Protocol Number: CRO-2012-17 Start Date*: 2012-09-28
    Sponsor Name:CENTRO DI RIFERIMENTO ONCOLOGICO DI AVIANO
    Full Title: Phase II clinical study on the efficacy and safety of procedural analgesia of oral transmucosal fentanyl citrate in oncologic patients eligible to permanent central venous catheter
    Medical condition: Cancer patients eligible to permanent central venous catheter due to chemotherapeutic treatment
    Disease: Version SOC Term Classification Code Term Level
    15.0 10042613 - Surgical and medical procedures 10053377 Central venous catheterisation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000874-36 Sponsor Protocol Number: 2014PAED13L Start Date*: 2015-10-30
    Sponsor Name:Norfolk and Norwich University Hospitals NHS Trust
    Full Title: The efficacy and safety of two topical antiseptic solutions for skin disinfection prior to percutaneous central venous catheter insertion in preterm neonates: a feasibility study
    Medical condition: Central venous catheter-related sepsis in premature neonates
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004862 10053212 Catheter sepsis LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001340-22 Sponsor Protocol Number: CathLockTrialHD Start Date*: 2020-02-24
    Sponsor Name:Universtitätsklinikum St.Pölten
    Full Title: A prospective, randomized, multicenter trial to compare a Taurolock™ based lock solution to a Citrate and Citrate/Urokinase based lock solution in tunneled hemodialysis catheters for the prevention...
    Medical condition: Patients requiring hemodialysis with a CVC due to renal failure of any cause. Aim of this study is to investigate different CVC lock Solutions.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-000801-25 Sponsor Protocol Number: RC06/21 Start Date*: 2021-12-10
    Sponsor Name:IRCCS MATERNO INFANTILE BURLO GAROFOLO
    Full Title: Intranasal dexmedetomidine: pilot pharmacokinetics / pharmacodynamics (PK/PD) study in a preterm population undergoing percutaneous central venous catheter placement
    Medical condition: Preterm newborns of less than/or equal to 36 weeks of gestational age who have an umbilical venous or arterial catheter which, for nutritional and/or therapeutic needs, must be replaced by a percut...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10049124 Sedation during medical procedure LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003194-24 Sponsor Protocol Number: CPI-226-03 Start Date*: 2006-01-02
    Sponsor Name:Cadence Pharmaceuticals, Inc.
    Full Title: Estudio en fase III, multicéntrico, aleatorizado, con enmascaramiento del tratamiento para el comité de evaluación para valorar la eficacia de la administración tópica de omiganán al 1,0% en gel en...
    Medical condition: Prevención de infecciones en la zona del catéter. Prevention of local site infections in patients requiring central venous and/or arterial catheterization and/or peripherally inserted central veno...
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004826-28 Sponsor Protocol Number: ict-bem-2004-02 Start Date*: 2005-03-28
    Sponsor Name:Instituto Científico y Tecnológico de Navarra
    Full Title: Multicenter double-blind placebo controlled aleatorized study to evaluate the efficacy and safety of bemiparin (3500 IU/day) in thromboprophylaxis in cancer paients with central vein catheter
    Medical condition: Deep Vein Thrombosis related central vein catheter (DVT-CVC)
    Disease: Version SOC Term Classification Code Term Level
    7.1 10051055 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-024597-19 Sponsor Protocol Number: CV185-079 Start Date*: 2011-06-21
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: Multiple-Dose Study Apixaban in Pediatric Subjects with an Indwelling Central Venous Catheter Revised Protocol 03, to incorporate Protocol amendments 1, 3 & 4
    Medical condition: Prevention of VTE in pediatric subject with a central venous cathether.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10043628 Thrombosis NOS LLT
    14.1 10047065 - Vascular disorders 10066899 Venous thromboembolism LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) NL (Ongoing) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2010-019984-12 Sponsor Protocol Number: AMNCH-TCD-CHG-1-2010 Start Date*: 2010-07-21
    Sponsor Name:Adelaide & Meath Hospital, incorporating The National Children's Hospital
    Full Title: A multicentre randomised trial comparing the effects of 2% chlorhexidine gluconate in 70% isopropyl alcohol as a skin, exit site and catheter hub cleansing agent versus other forms of chlorhexidine...
    Medical condition: Prevention of central venous catheter-related infections in haemodialysis patients. This trial will evaluate the effectiveness of 2% chlorhexidine gluconate in 70%isopropyl alcohol as a skin, exit...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001511-54 Sponsor Protocol Number: A5951060 Start Date*: 2004-12-08
    Sponsor Name:Pfizer Global Research and Development
    Full Title: Linezolid vs. Vancomycin/Oxacillin/Dicloxacillin in the Treatment of Catheter-Related Gram Positive Bloodstream Infections.
    Medical condition: Catheter related gram positive bloodstream infection
    Disease: Version SOC Term Classification Code Term Level
    10007810 LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002896-32 Sponsor Protocol Number: D5136C00001 Start Date*: 2013-01-16
    Sponsor Name:AstraZeneca AB
    Full Title: A multicenter, double-blind, placebo-controlled, pharmacokinetic, pharmacodynamic, safety and tolerability study in patients aged 12 to <18 years of age with a central venous catheter to support pr...
    Medical condition: Thrombosis, thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    14.1 10005329 - Blood and lymphatic system disorders 10050661 Platelet aggregation inhibition PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Ongoing) FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001845-15 Sponsor Protocol Number: TINCRBEL_study Start Date*: 2018-07-13
    Sponsor Name:Academic medical centre, department of internal medicine
    Full Title: EvaluaTion of Clinical and laboratory outcomes of Rivaroxaban in short Bowel syndrome patients dEpending on Long term parenteral nutrition: a prospective cohort study (TINCRBEL study)
    Medical condition: Chronic intestinal failuyre (IF) is caused by large surgical bowel resection, severe motility, or absorption diseorders. These patientds require partial or total parenteral nutrition (PN and TPN, r...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015163-14 Sponsor Protocol Number: 73191198 Start Date*: 2010-01-08
    Sponsor Name:Department of Pediatrics Aarhus University Hospital Skejby
    Full Title: Reduction of hypertrophic scars and keloid by use of corticosteroid cream after removal of a tunneled central venous catheter in childhood cancer survivors
    Medical condition: Development of hypertrophic and keloid scars after removal of tunneled central venous catheters in childhood cancer survivors
    Disease: Version SOC Term Classification Code Term Level
    12.0 10020879 Hypertrophic scar LLT
    12.0 10023330 Keloid scar LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002124-32 Sponsor Protocol Number: CUSA-081-HEM-01 Start Date*: 2020-01-02
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: READY 1: A Phase 3, Randomized, Double-Blind, Active and Placebo-Controlled Study on the use of CUSA-081 for Dysfunctional Central Venous Access Devices (CVADs)
    Medical condition: Catheter Occlusion Thrombosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) ES (Prematurely Ended) RO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002158-59 Sponsor Protocol Number: SÖSPN Start Date*: 2018-09-05
    Sponsor Name:Södersjukhuset
    Full Title: A prospective study of the safety of peripherally administered norepinephrine during surgery
    Medical condition: Hypotension during general anaesthesia or central blockades
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000595-32 Sponsor Protocol Number: Ematonco/divmalinf/2006.1 Start Date*: 2006-09-06
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: Rescue therapy for indwelling central venous Hickmann-Broviac catheter related infections with antibiotic lock technique
    Medical condition: Patients with Hemato-oncologic disease or undergoing Hematopoietic stem cell transplantation
    Disease: Version SOC Term Classification Code Term Level
    6.1 10003997 PT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000675-15 Sponsor Protocol Number: 06RP02 Start Date*: 2006-09-11
    Sponsor Name:Great Ormond Street Hospital for Children NHS Trust
    Full Title: Open label Randomised Controlled Trial comparing povidone-iodine 10% with alcohol and 0.5% chlorhexidine with alcohol for prevention of early infection associated with insertion of central venous a...
    Medical condition: Potential Systematic Sepsis
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-010190-20 Sponsor Protocol Number: 0908010 Start Date*: 2009-04-22
    Sponsor Name:CHU Saint-Etienne
    Full Title: DETECTION OF ACUTE RENAL FAILURE IN CRITICALLY ILL PATIENTS: A prospective evaluation of cystatin C diagnostic performance
    Medical condition: critically ill patients hospitalised in inetnsive care unit
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10022519 Intensive care PT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000545-19 Sponsor Protocol Number: HA008 Start Date*: 2006-08-03
    Sponsor Name:Nuvelo, Inc.
    Full Title: Phase 3, Multicenter, Multi-National, Open-Label Study to Evaluate the Safety and Efficacy of Alfimeprase in Subjects with Occluded Central Venous Access Devices
    Medical condition: Central venous access device withdrawl occlusion
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051149 Catheter occlusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-003843-28 Sponsor Protocol Number: STH13565 Start Date*: 2005-03-18
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: The acute effects of testosterone administration in patients with pulmonary hypertension
    Medical condition: Pulmonary Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-002094-55 Sponsor Protocol Number: 1861 Start Date*: 2019-09-09
    Sponsor Name:Universitair Ziekenhuis Brussel, Belgium
    Full Title: Safety and feasibility of S-Caine patch use in children under the age of three
    Medical condition: children under the age of three that are in possession of a central catheter and under permanent monitoring (healthy, or any condition)
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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